Seth Rogen on Getting High with Paul McCartney, Sexy Scene with Penélope Cruz & First Colonoscopy

Jimmy Kimmel Live · 15:56

175,621 views · 4,179 likes · Jul 16, 2026

Seth talks to Guest Host Ike Barinholtz about the first time they met, Ike embarrassing him when they were smoking pot with Paul McCartney at the SNL afterparty, shooting season two of The Studio, getting his first colonoscopy, his movie The Invite, filming sexy scenes with Penélope Cruz, and getting another Emmy nomination for The Muppet Show.

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Seth talks to Guest Host Ike Barinholtz about the first time they met, Ike embarrassing him when they were smoking pot with Paul McCartney at the SNL afterparty, shooting season two of The Studio, getting his first colonoscopy, his movie The Invite, filming sexy scenes with Penélope Cruz, and getting another Emmy nomination for The Muppet Show.

SUBSCRIBE to get the latest #Kimmel: http://bit.ly/J…

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